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Given that, the sensible position is to treat the drug-interaction contraindications as firm, particularly antidepressants and stimulants, while accepting that for someone on no such medications the risk is likely small but genuinely unquantified

Vitamin B12 is essential for the production of red blood cells, DNA synthesis, neurological function, and the maintenance of the nervous system

Vitamin B12 for Athletes: Dosing and Evidence (2026): The Short Answer Vitamin B12 (cobalamin) is essential for red blood cell production, oxygen delivery, and nerve function, all of which directly affect endurance performance

Additionally, other factors such as having had gastric bypass surgery or taking antacids long-term can lead to deficiency

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