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Side Effects: The Critical Difference Melanotan-1 Side Effects MT-1's selective MC1R binding means a very clean side effect profile: Mild facial flushing (most common, transient) Slight nausea (rare at standard doses) Injection site redness (minor, fades quickly) Headache (uncommon) In clinical trials for EPP, serious adverse events were rare and MT-1 was generally well tolerated over extended use periods (Langendonk et al., 2015)

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