Interestingly, the combination of semaglutide and trevogrumab alone (without garetosmab) was better tolerated, with discontinuation rates similar to semaglutide monotherapy, suggesting that garetosmab may contribute to the increased side effects in the triplet regimen
The muscle loss with GLP-1 is real and the risks of sarcorpenia are real as we go into the future, so it is important to have guidance in this at Prevention Clinics
29.Prado CM, Phillips SM, Gonzalez MC, Heymsfield SB
If you have unused 2.5mg pens after escalating to 5mg, store them in the refrigerator
David Hornigold, Jacqueline Naylor and Alessandra Rossi (MedImmune, Cambridge, UK), and used as described elsewhere(38)