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This review sets out the molecular and central nervous system biology of the GLP-1 receptor, the mechanisms proposed to underlie its neuroprotective effects, and the clinical trial record in Parkinsons and Alzheimers disease
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For the measurement of GSH binding affinity, samples were applied to GSH-Sepharose beads (GE Healthcare) and incubated for 30 min at RT by rotating
However, because the drug affects several parts of the digestive system, many of its side effects are gastrointestinal in nature
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