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However, a recent meta-analysis including eight observational studies revealed increases in cardiovascular and gastrointestinal disorders, and in mortality with regular intake of high therapeutic doses ( Reference Roberts, Delgado Nunes and Buckner 15 )
This study aimed to assess the cardiovascular safety of semaglutide, a glucagon-like peptide 1 analogue, in patients with type 2 diabetes
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If your provider prescribed a GLP-1 agonist for you, know that while it can decrease appetite and promote weight loss, your provider may take a comprehensive approach that also includes exercise, diet changes, behavioral modifications, or sometimes even bariatric surgery
46 Notably, injection site reactions occur at low rates: 1 to 2 percent with semaglutide, 1 to 3 percent with dulaglutide, and 22 percent with once-weekly exenatide
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