This small molecule compound demonstrates exceptional ability to block nicotinamide N-methyltransferase enzyme activity, preventing NAD+ depletion while activating sirtuin pathways associated with healthy aging and metabolic optimization
Careful examination of the published literature does suggest that ketamine is useful in treating neuropathic pain conditions, for example, trigeminal neuralgia, post-herpetic neuralgia, complex regional pain syndrome, and fibromyalgia
doi:10.1007/s00228-025-03869-9 Nazmy A, Sobhy A, Elshahat A, et al
Panminerva medica, 53 (3 Suppl 1), 65-70
Safety, Limits, and Caveats The physiological review focuses on normal intrinsic factor function and may not fully address all pathological conditions affecting its production or function