Wang T, Tomas D, Perera ND, Cuic B, Luikinga S, Viden A, et al
PMCID: PMC9556195
in: PubMed | Google Scholar | Published April 21, 2020 - More info Discovery strategies commonly focus on the identification of chemical libraries or natural products, but the modulation of endogenous ligands offers a much better therapeutic strategy due to their low adverse potential
It activates sirtuins, the longevity-associated proteins that regulate cellular aging, and it powers PARP enzymes, which are responsible for DNA repair
The consistent finding across these studies is that BPC-157 promotes maintenance of the gastric mucosal barrier and accelerates healing of established lesions, effects that are consistent with the peptide's origin in human gastric juice