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Renoprotective effects of metformin are independent of organic cation transporters 1 & 2 and AMP-activated protein kinase in the kidney
I reflected on a similar point in a post this morning: how interventions that dont address underlying metabolic regulation often lead to short-term success but long-term instability
"Countries such as Brazil and China are major pharmaceutical manufacturing hubs that will be able to quickly scale production of generic medications
The results paved the way for liraglutide, branded as Saxenda, to be approved in the US as a once-a-day subcutaneous injection in December 2014 and in Europe in 2015 for the treatment of chronic weight management combined with a reduced calorie diet and increased physical exercise (Molteni, Chen)
