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Because your body naturally produces glutathione, its levels fluctuate throughout a 24-hour cycle

48 : 225238 Fong TM, McNamee MG

This isn't a minor discrepancy

Moreover, Se -mediated GPX4 regulation and neuronal protection are extremely complex and therefore difficult to successfully translate into the clinic ( DFO reversed the survival of IPF mice, it still suffers from low solubility and targeting during delivery (Guo et al., 2023)