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Studies show that weight regain can occur if the medication is discontinued, as the underlying biological factors that led to weight gain may return
R Substrates acetylated by NATs include: Aromatic amine carcinogens (beta-naphthylamine, 4-aminobiphenyl, benzidine) Caffeine (partially, via NAT2) Dapsone Hydralazine Isoniazid (tuberculosis drug) Para-aminosalicylic acid (PABA) Procainamide Sulfonamide antibiotics Acetylation can also produce bioactivation
This discrepancy might be attributed to the complex, multifaceted nature of stress, which can be influenced by a wide array of factors beyond the scope of our intervention [55]
If medication side effects are limiting progress, or if weight returns after stopping, bariatric surgery may provide a more lasting solution
Study team and theoretical perspective The study was conducted by a cross-disciplinary team, with expertise in psychology (MB), diabetes (KI, PSG, AP) and psychiatry (KI, AP)
