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Description

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Mercapturate pathway metabolites of sotorasib, a covalent inhibitor of KRAS(G12C), are associated with renal toxicity in the Sprague Dawley rat

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The physiological basis of our model is the reaction diagram [Figure 1] and the K m values for the enzymes

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Dosage matched to delivery method matched to goal

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Journal of Agricultural and Food Chemistry, 67 (10), 2754-2762

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