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Minnaar, P
These hormones naturally occur in the body and are responsible for regulating appetite and blood sugar
Cytoprotective effects on the gastric mucosa have been studied in both alcohol-induced and NSAID-induced injury models, which is directly relevant to the canine clinical context where NSAID gastropathy is a common presentation
Currently, there is an ongoing randomised double-masked placebo-controlled trial, the SUMMIT trial, studying the efficacy and safety of tirzepatide, a dual agonist of glucose-dependent insulinotropic polypeptide and GLP-1 receptors, versus placebo in HFpEF patients with obesity (NCT04847557)
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