[200] [202] As of January 2026, protein kinase A (PKA), protein kinase C (PKC), Ca2+/calmodulin-dependent protein kinase II (CaMKII), and Ras homolog family member A (RhoA) have all been demonstrated experimentally to regulate monoamine transporter function activity following amphetamine exposure
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M., Ritt, M., Dysthe, M., Malik, R
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It can also be associated with excess alcohol consumption, certain medications, and less commonly, high levels can indicate acute inflammation of the pancreas (pancreatitis)