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Blocks glucagon secretion: When your body needs to raise your blood sugar levels, it uses glucagon

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These symptoms are primarily due to the mode of action of GLP-1 RAs on the gut, as a GLP-1 may directly or indirectly regulate electrolyte and fluid homeostasis by influencing feeding and drinking behavior as well as electrolyte transport in the kidneys and gastrointestinal tract [25]

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Most of this weight loss occurs within the first 68 to 72 weeks of treatment, so patience and consistency are key