Yes, periodic maintenance sessions may be required to sustain the results achieved through glutathione shots
In particular, aerobic respiration by mitochondria (the powerhouses of the cell) leads to the production of ROS as oxygen is gradually converted into water
So the body repairs itself
Further randomized controlled trials are necessary to fully evaluate its efficacy in hyperpigmentation, TEWL, skin elasticity, and ultraviolet (UV) damage
To boost glutathione levels, people may consider consuming foods rich in the amino acids required for its synthesis, such as cysteine-containing foods (e.g., garlic, onions, cruciferous vegetables) or take glutathione supplements (though the effectiveness of oral supplementation is debated)