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Some people on semaglutide notice an increased heart rate and palpitations, episodes that can be distressing if they recur

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Pinna A, Ragaisyte I, Morton W, Angioletti-Uberti S, Proust A, DAntuono R, Luk CH, Gutierrez MG, Cerrone M, Wilkinson KA, Mohammed AA, McGilvery CM, Surez-Bonnet A, Zimmerman M, Gengenbacher M, Wilkinson RJ, Porter AE

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Tirzepatide follows a similar pattern with steps at 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg, and 15mg, requiring potentially six escalation periods