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If pregnancy is planned, the medication should be discontinued at least two months before attempting conception due to the long washout period of semaglutide
In REDEFINE 1 (NEJM 2025, n=3,417, 68 weeks), cagrilintide monotherapy at 2.4 mg produced 11.8% mean body-weight reduction versus 2.3% with placebo
However, some people may experience redness, itching, or irritation
Store in a dry environment, in a well-closed container at a temperature of up to 25C, out of reach of small children
(download DOCX Tables S1-S2 and Figures S1-S12 Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made
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