ema prac naion semaglutide very rare side effect 2025 says Ozempic, Wegovy may cause eye condition By Investing.com Semaglutide from Bench to Bedside:

A randomized controlled trial using a fractional factorial design showed that compared with placebo, the combined supplementation with riboflavin (3 mg/day) and niacin (40 mg/day) for five to six years reduced the prevalence of nuclear cataract but increased the progression of posterior subcapsular cataracts in population affected by multiple nutrient deficiency living in rural China (38)

A key difference between these medications is that Mounjaro mimics GLP-1 and GIP, whereas Ozempic only mimics GLP-1

GLP-1 receptor agonists, like semaglutide and liraglutide, work like this hormone does

Lilly says it plans full presentation at a scientific congress later this year, and the FDA filing will follow on a schedule the company has not yet specified publicly

Experimental receptor assays demonstrate that GLP-RT functions as an agonist at all three receptors, although the peptide exhibits differing potency levels across the receptor set