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Authors' contributions JC made substantial contributions to conception and design of the study, acquisition, analysis and interpretation of data, revised the manuscript critically for important intellectual content, and was a major contributor to writing the manuscript

Bioavailability approaches 100%

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Research published in the Journal of Biological Chemistry identified its role in wound repair and collagen synthesis [1]

Among these, esculetin (ESC), a naturally occurring coumarin derivative also known as 6,7-dihydroxycoumarin, distinguishes itself by a comprehensive spectrum of biological activities