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In addition, an increasing amount of research has supported a pathophysiological role for ferroptosis in the development of cardiovascular diseases, including myocardial ischemiareperfusion injury, myocardial infarction, adriamycin-mediated myocardial injury, and heart failure [69]
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A few possible relevant articles were excluded due to language issues
The compound was also investigated as PL14736 in early-phase IBD clinical work, as described in a 2008 paper by Klicek and colleagues in Journal of Pharmacological Sciences , though that clinical program was never completed or approved
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