Long-term studies in mice show that Epithalon administration significantly extended maximum lifespan by 12.3% and increased the lifespan of the last 10% of survivors by 13.3% compared to control groups, while showing no adverse effects on body weight or food consumption
Because of poor renal clearance, the B12 remained in the blood, and levels rose from an average of 422 pmol/L to 54,000 pmol/L
No claims are made regarding treatment, cure, or diagnosis of any disease
Historically, sex-specific signaling was often treated as a confounder to be avoided
Elevated levels of homocysteine are correlated with several pathologies, and are recognized as an initiating factor for arteriosclerosis of coronary, cerebral and peripheral vessels (Boushey et al., 1995