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78 Although ALDH1L1 is overexpressed in NSCLC and GC cancer, 79,80 ALDH1L1 is reported profoundly downregulated or silenced in cancers, rendering it a candidate tumor suppressor

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This is a different approach and the early outcomes being studied are strong enough to make experts curious about whether the triple mechanism can translate into meaningful real-world benefits once larger trials confirm safety and long-term results

Mouse kidney functions were assessed by measuring serum creatinine and blood urea nitrogen levels (DICT-500 and DIUR-500, respectively, Quantichrome, BioAssay Systems) according to the manufacturers protocol