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Storage: Lyophilized: store frozen at 20 C (4 F)

Moreover, in vitro cell culture experiments have confirmed that the correlation between GLP-1RA and pancreatic cancer may be related to its ability to induce phenotypic transformation of pancreatic exocrine cells into pancreatic endocrine cells (80, 81)

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This can lead to the formation of bone spurs that push into the spinal canal, reducing the available space

Practical guidance: check a basic metabolic panel (BMP) at baseline and again 7-14 days after starting prednisone in any patient on losartan, especially if the patient has an eGFR below 60 mL/min/1.73m or is concurrently taking an NSAID or diuretic