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Rat liver peroxisomes, II

The SELECT trial enrolled 17,604 patients with a mean body mass index (BMI) of 33.3 and preexisting cardiovascular disease (prior heart attack, stroke, or peripheral artery disease) but no diabetes

There has never been any medication that has been this effective, and the benefits are comparable to metabolic (bariatric) surgery, which remains the best evidence-based weight loss method

Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): A double-blind, randomised, phase 3 trial

GLP-1 works its weight-loss magic by mimicking the effects of natural hormones in regulating metabolism