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Upon UVR exposure, these compounds react to produce reactive oxygen species (ROS), which have the potential to readily oxidise circulating folates
(PubMed) Tiemeier H, van Tuijl HR, Hofman A, Meijer J, Kiliaan AJ, Breteler MM
In one trial, 16 people placed on experimental bed rest for 3 weeks (in order to increase urinary calcium excretion by causing bone breakdown) and treated with 20 mg per day of the bisphosphonate alendronate had lower urine calcium concentrations, and lower calcium oxalate and calcium phosphate saturations, compared with placebo (Ruml 1995)