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GLP-3 Lets break down the key differences in a clear, comparative format: Primary Location of Action GLP-1: Pancreas, brain, stomach, cardiovascular system GLP-2: Intestinal tract, gut epithelium GLP-3: Unknown/under investigation Main Functions GLP-1: Regulates blood sugar Suppresses appetite Promotes weight loss Slows gastric emptying Protects cardiovascular system GLP-2: Promotes intestinal growth Enhances nutrient absorption Repairs gut lining Reduces inflammation Strengthens gut barrier GLP-3: Functions not well established Potentially metabolic or intestinal Requires more research Clinical Applications GLP-1: Type 2 diabetes treatment Obesity and weight management Cardiovascular disease prevention Potential neuroprotection GLP-2: Short bowel syndrome Inflammatory bowel disease (experimental) Intestinal injury recovery Malabsorption disorders GLP-3: No established clinical applications Currently research-only Half-Life GLP-1: Very short (2 minutes for natural form

Bakuchi oil (Psoralea corylifolia) and sesame oil are used, which contain psoralen to stimulate melanocytes under UV light

Diabetes Res Clin Pract (2016) 121:1726