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The detected correlation may alternatively stem from unmeasured variations in patients baseline vascular health, advanced metabolic severity, or underlying diabetic complications, rather than a direct cellular effect of the GLP-1 molecules themselves

Mechanisms of disease: inflammatory bowel diseases

Based on these retrospective analyses, one could argue that all newly diagnosed, as well as established, type 2 diabetes patients should be started simultaneously, within a few weeks to months, on an SGLT2 inhibitor plus a GLP-1 receptor agonist

In PEGylation, polyethylene glycol (PEG) chains are attached