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Second, pre-treatment liver function tests and complete blood count are mandatory before the first session, with repeat LFTs every 4 to 6 sessions

It helps to separate two different meanings of the word work. A peptide can be biologically active (it binds its receptor and produces an effect) yet have terrible oral bioavailability (almost none of it reaches the receptor when swallowed)

The following comparison summarizes the key considerations: For patients with intact GI absorption, oral high-dose supplementation (1,000 to 2,000 mcg daily) provides a convenient and cost-effective path to correcting deficiency

Tapering approach: Reduce by 25-50% every 2-3 months while tracking weight stability

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