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For example, in a study of almost 17,000 people published in JAMA Ophthalmology in 2024, researchers found an increased risk of NAION among individuals prescribed semaglutide relative to those prescribed other medications to treat type-2 diabetes and obesity

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If you experience severe vomiting or diarrhea during dose escalations, the mechanical absorption of oral medications may be compromised

The drug class has also seen Novo Nordisk overtake luxury fashion brand LVMH as Europes most valuable company, propping up Denmarks GDP in the process