Skin aging (reduced collagen, wrinkles): Fibroblasts lose repair capacity, leading to extracellular matrix degradation
It also shows strong potential in more therapeutic applications from pain reduction to nervous system function, although research is ongoing at this time
Bauman WA, Shaw S, Jayatilleke E, Spungen AM, Herbert V (2000) Increased intake of calcium reverses vitamin B12 malabsorption induced by metformin
Importantly, this report was authored by physicians affiliated with a clinic selling BPC-157 injections, presenting a clear conflict of interest
This mechanistic complementarity BPC-157 governing tissue organisation and vascularisation, TB-500 governing cellular movement and cytoskeletal reconstruction is what makes the combination a subject of sustained research interest beyond either peptide studied in isolation