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Here is a quick breakdown before the details: All three are FDA-approved sites for subcutaneous semaglutide injection
doi: 10.1016/j.molmet.2019.09.010 12 BaggioLLDruckerDJ
But in general, turning a peptide (including GLP-1 or insulin) into an oral formulation means overcoming three major challenges: protecting the peptide from digestion in the stomach, improving absorption of the peptide via the gut, and slowing down the enzymatic breakdown and excretion of the peptide once it is in the blood
I, as a physician, want a simpler prescribing pathway
Habimana et al., 2020)
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