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Growth-hormone secretagogues Mechanism and evidence: GH secretagogues work upstream of growth hormone itself, stimulating GH release from the pituitary either by mimicking GHRH (CJC-1295, tesamorelin) or by activating the ghrelin receptor (ipamorelin)
International Journal of Women's Health, 17 , 40574073
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Sermorelin is a standalone GHRH(1-29) fragment with a very short half-life (~11-12 minutes) and acts only on the GHRH receptor
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