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Similarly, a meta-analysis of nine observational studies in older adults found low serum vitamin B 12 concentration to be associated with increased risk for depression, with significant association only in women (100)

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Oral BPC-157 can be useful for gut mucosal support, but it should be paired with attention to food triggers, alcohol intake, NSAID use, stress physiology, microbiome health, sleep, and appropriate GI evaluation when symptoms warrant it

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