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Short term hypoxic exposure (2h-4h) did not showed any major effect on lung architecture but with increased duration of exposure (8h-16h) deformities in lung parenchyma were observed, leading to development edema during 24h-48h of exposure

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For high-risk patients, alternatives such as dietary modifications may provide safer synergies with conventional therapies, potentially enhancing treatment safety and efficacy (107)

S-Adenosyl-L-Methionine (SAMe) Plays a complex role in metabolism, functioning as a methyl group donor ( transmethylation reactions ), precursor of sulphur-containing compounds (transsulfuration pathway) , and in production of polyamines