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In February 2026, the FDA released a report alerting patients and providers about the risks of compounded GLP-1 medications

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Cardiometabolic complications are inside the indication, not adjacent to it

Anxiety or mood changes are not among the most commonly reported Mounjaro side effects, but any new or worsening mood symptoms should be taken seriously

For example, ALS presents both sporadic and familial forms, often linked to defective DNA repair, which leads to neuronal damage, premature aging, and subsequent neurodegeneration (56)