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doi: 10.1530/eje.0.143R007 252 ArvatEDi VitoLBroglioFPapottiMMuccioliGDieguezCet al

Sheth KR, Keays M, Grimsby GM, Granberg CF, Menon VS, DaJusta DG, Ostrov L, Hill M, Sanchez E, Kuppermann D, Harrison CB, Jacobs MA, Huang R, Burgu B, Hennes H, Schlomer BJ, Baker LA (2016) Diagnosing Testicular Torsion before Urological Consultation and Imaging: Validation of the TWIST Score

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The rate of loss accelerates during the dose escalation phase and typically peaks around weeks 16-32 when you reach higher maintenance doses