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The positive charge because of Dioleoyl-3-trimethylammonium propane (DOTAP), on the surface of the liposome, improved its affinity for the anionic skin membrane resulting in enhanced efficiency in a psoriatic plaque model induced by imiquimod (IMQ) [324]
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The protective effects of glutathione amino acid precursors were further underscored when cells were challenged with menadione, a known inducer of oxidative stress
This finding is uniformly pathologic, is more common in men than women 69 and, when present, manifests with osteopaenia and fractures in up to 47% of patients 20
Furthermore, omega-3 PUFAs protect retinal tissues by alleviating oxidative damage through their intrinsic antioxidant mechanisms (44, 45)
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