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PMID: 28340044 Falutz J, et al
These needle-shaped crystals can accumulate in diverse tissues, particularly in joints, eliciting an innate immune response
it can be catastrophic
These patients should be followed more closely ( Table 1 )
One randomized placebo-controlled trial that assessed the effect of oral lipoic acid supplementation in 58 patients diagnosed with metabolic syndrome, a condition characterized by abnormal glucose and lipid metabolism, showed that flow-mediated vasodilation improved by 44% with 300 mg/day of lipoic acid for four weeks (66)
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