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For positions V12 and F112, many of the tested variants exhibited wild-type-level dehydratase activity (Fig
*Lu : Sn phm khng phi l thuc v khng th dng thay th thuc tr bnh
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On the other hand, this recently evolved transcriptional network can precisely regulate the entire process of biofilm formation through the coordinated binding of downstream target genes, and its interaction mode and the specificity of target gene selection reflect the adaptive evolution characteristics of this network, providing a core mechanism framework for understanding the pathogenicity and drug resistance of C
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