In PD models, BDNF promotes the survival of dopaminergic neurons, enhances dopaminergic neurotransmission, and improves motor performance 29
Basic health screening should be conducted to check for conditions that make GLP-1 medications unsafe, such as certain thyroid conditions, pancreas problems, or severe digestive issues
Patients often find that nausea and digestive issues become less frequent and less intense
References SURMOUNT-1 Clinical Trial: The primary source for the weight loss data on tirzepatide, published in The New England Journal of Medicine
Psychiatry Times, Vol 42, Issue 7.) The potential for GLP-1 receptor agonists to impact addictive behaviors is certainly intriguing, particularly given the significant morbidity associated with substance use disorders