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GLP-1 medications discussed in this article are prescription medications that require evaluation by a licensed clinician

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The area under the tongue has a rich supply of blood vessels, which allows the medication to bypass the digestive system and liver, leading to faster and more efficient absorption compared to oral medications that are swallowed

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Sardeli AV, Komatsu TR, Mori MA, Gspari AF, Chacon-Mikahil MP

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However, the discontinuation rates for Danuglipron across different doses were over 50%, significantly higher than the approximately 40% observed in the placebo group, indicating poor tolerability in some patients

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1b and Extended Data Fig

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