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Last reviewed: June 8, 2026 Last updated: June 8, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
More than 40 alkaloids have been identified in Mitragyna speciosa, the major constituent being mitragynine, which is exclusive to this plant
While GLP-1 and GIP primarily regulate insulin secretion and appetite pathways, the addition of glucagon receptor signaling actively allows researchers to study direct increases in cellular energy expenditure, enhanced lipolysis, and accelerated hepatic lipid metabolism
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GIP (Glucose-Dependent Insulinotropic Polypeptide) Another incretin hormone that influences insulin secretion and may affect fat metabolism
