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This is even more important since FMN and FAD are integral components of the electron transport chain (ETC), a vital part of cellular respiration
To exclude the possibility that GSH is cleaved by enzymes to release glutamate for Ca signal propagation, we employed GGsTop, a well-known chemical inhibitor that specifically targets gamma-glutamyl transpeptidase (GGT), the enzyme responsible for converting GSH to Glu 26
This region shows an electron density high enough for constructing main-chain atoms (Fig 1A and 1C)
W.EmotoC.FukudaT.MizunoT.MehtaP
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