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With the popularity of GLP-1 agonists ever-increasing and over 150 GLP-1 drug candidates in development [3], the field is continually expanding, most recently into oncology and obesity-related cancers.[4] While most approved GLP-1RAs require subcutaneous injection, substantial work is being undertaken to move toward oral GLP-1 therapies [5], such as Rybelsus which was the first oral GLP-1RA approved by the FDA in 2019

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This distinction also separates a compounded drug from a generic one: While the latter has an abbreviated FDA-approval process (since the existing brand-name drug has already been shown safe and efficacious), the maker still has to prove to the FDA that their version is equivalent to the OG on both fronts