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However, there are several challenges towards it, namely: (1) further in-depth understanding of mechanisms involved in CS-induced vascular and cerebrovascular impairments

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Lysine Catabolism via the Saccharopine Pathway There are several, at least three, pathways for lysine catabolism but the primary pathway utilized within the liver of humans is one that begins with the formation of an adduct between lysine and 2-oxoglutarate (-ketoglutarate) called saccharopine