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The choice between them depends not just on your goals but your body, your medical history and your doctors guidance because in the end, the smartest way to lose weight might not be the fastest

Of the 24 participants who completed the trial, the maximum tolerated dose of semaglutide was 0.25 mg in two (8.3%) participants, 0.5 mg in six (25.0%) participants and 1 mg in 16 (66.7%) participants

If fatigue becomes problematic at any stage, holding at the current dose for an additional two to four weeks before increasing often resolves the issue