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A 50 mg vial reconstituted with bacteriostatic water yields about 12.5 mg/mL

A still unsolved issue, connected with the role of carnitine in modulating gene expression (Figure 1) is the link between mitochondria and nucleus: acetylcarnitine produced in mitochondria would reach the nucleus providing acetyl units (Figure 2)

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However, because the study was not blinded, placebo-controlled, or randomized, it's not possible to determine if Pycnogenol actually improved symptoms

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