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Reaching the highest dose possible is not essential if a lower dose is effective for you

hypothesized that neuroprotective effects of Ex-4 may occur through either GLP-1R-dependent or -independent pathways, in a dose-dependent manner (93)

In this regard, Figure 1 shows that certain gut microbes produce metabolites that stimulate L cells to release GLP-1, PYY (Peptide YY), and serotonin, helping regulate appetite, metabolism, and energy balance while sending signals to the brain via the vagus nerve