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Physiology (Bethesda, Md

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It has three primary pathways of antioxidant activity: 1) Directly neutralizing oxidative molecules through a redox reaction 2) Functioning as a cofactor of the peroxide neutralizing enzyme Glutathione Peroxidase 3) Supporting other antioxidants such as Vitamin C and Glutathione for General Health Glutathione also has non-antioxidant related protective and detoxification benefits

Adverse events such as increased blood calcitonin, goiter and thyroid tumor may occur

Therefore, inhibiting SLC7A11 can interfere with the synthesis of glutathione in tumor cells and disrupt the oxidative-reductive homeostasis of cancer cells (Zhang et al., 2018)