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Peter de Keizer's pioneering research at Erasmus University Medical Center to its current status as a leading senolytic research tool, FOXO4-DRI demonstrates how precise molecular targeting can enable selective elimination of harmful cellular populations while preserving healthy tissue function

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Further supporting this, Lock and colleagues demonstrated that glutathione protects against 2-chloropropionic acid (CPA)-induced cerebellar toxicity by preserving thiol redox equilibrium and potentially interacting with NMDA receptor-mediated pathways

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Animal studies show mostly mild local irritation at injection sites